Diaper dermatitis (napkin rash) is a skin disease which can be seen in diaper areas of babies as rubor and in more serious cases as bulla and open wounds. For treatment in necessary conditions, it is suggested to use Antifungals and/or -1% hydrocortisone pomads in addition to symptomatic therapy such as moistening of the skin and removal of irritant agents from area. Seven-months-girl and six-months-boy case was brought with excess weight intake complaints. They were excessivly obese and had an increase adipose tissue under their skins. Both cases had used pomads involving clobetasol 17-propionate for the last 3 months. Their family history was normal. Serum ACTH levels was
In experiments on various animals glyderinine, a derivative of glycyrrhizic acid isolated from Glycyrrhiza glabra, was found to exert a pronounced anti-inflammatory effect exceeding that of hydrocortisone and amidopyrine. The mechanism of the anti-inflammatory effect was to a certain degree related to the adrenal cortex, suppression of vascular permeability and antagonism to inflammation as well. Similarly to other anti-inflammatory agents, glyderinine possesses analgesic and antipyretic properties, but unlike them it fails to suppress hemopoiesis and to cause ulceration of the gastrointestinal mucosa. The drug is of low toxicity and exerts the antiallergic effect. Glyderinine was successfully tried and recommended for a wide use as an ointment for treating skin diseases.
The cornea has two primary functions: an optical interface that transmits and refracts light and a barrier to the external environment. However, maintenance of one sets up challenges for the other. The external cornea is part of the ocular surface mucous membrane; however, unlike most other mucous membrane-derived tissue, the cornea has no local lymphoid tissue, few native immune cells and no local vascular supply. Presence of any of these at high levels would enhance corneal barrier function through increasing access to the immune response, but would result in a loss of corneal clarity and reduced optical function. However, the absence of these features from the central cornea limits the cornea’s ability to function as a barrier. If the cornea develops an infection, the immune system is initially unable to help, which allows for early unfettered proliferation of the microbe.