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There is only one extant manuscript of Candide that was written before the work's 1759 publication; it was discovered in 1956 by Wade and since named the La Vallière Manuscript . It is believed to have been sent, chapter by chapter, by Voltaire to the Duke and Duchess La Vallière in the autumn of 1758. [4] The manuscript was sold to the Bibliothèque de l'Arsenal in the late eighteenth century, where it remained undiscovered for almost two hundred years. [30] The La Vallière Manuscript , the most original and authentic of all surviving copies of Candide , was probably dictated by Voltaire to his secretary, Jean-Louis Wagnière , then edited directly. [27] [31] In addition to this manuscript, there is believed to have been another, one copied by Wagnière for the Elector Charles-Théodore, who hosted Voltaire during the summer of 1758. The existence of this copy was first postulated by Norman L. Torrey in 1929. If it exists, it remains undiscovered. [27] [32]

I am a Registered Nurse of many years experience working with the Eastern Regional Health Authority of the Republic of Trinidd and Tobago in a supervisory position.
I have never experience such a disaster but praise and thanks to the Almighty for the strength, life and the ability of yourself, nurses, other members of staff and the public who assisted at this time.
I do not know what you have gone through but congratulations to you and your team for what you have done. Thank God for keeping you alive to take care of the wounded. May the Almighty truly bless you, Dr Kikta, the Nurses and all others who assisted on that fatal day. Keep the mantle flying. Congratulations, God Bless.

Over the past two decades, elegant work from Dr. R. Shoemaker and his colleagues has demonstrated unequivocally that biotoxins such as mycotoxins are associated with a broad range of symptoms, including cognitive decline (summarized in [5]). These researchers and clinicians identified a constellation of symptoms, signs, genetic predisposition (HLA-DR/DQ haplotypes), and laboratory abnormalities characteristic of patients exposed to, and sensitive to, these biotoxins. The resulting syndrome has been designated chronic inflammatory response syndrome (CIRS).

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