In the past several years, some newer medications have come on the market; these are commonly referred to as COX-2 inhibitors . Remember, all NSAIDs work against cyclooxygenase (COX). Traditional NSAIDs (. Ibuprofen, Motrin, Aleve) work against both COX-1 and COX-2. COX-1 and COX-2 are both types of cyclooxygenase enzymes that function in your body. The new medications (. Celebrex) work primarily against COX-2, and allow COX-1 to function normally. Because COX-1 is more important in producing the protective lining in your gut (gastric mucosa), these newer NSAIDs are believed to have less of a risk of causing stomach ulcers.
In most countries, misoprostol can be purchased in pharmacies as Cytotec or under some other trade name as an anti-ulcer medication. Some pharmacies may ask for a medical prescription for this purpose. Buying so-called “abortion drugs” on the black market or from unknown Internet sources is not recommended. Women can also purchase the combined mifepristone-misoprostol regimen online from Women on Web in the Netherlands ( http:// ) with a donation of 70-90 Euros (exceptions are made in difficult cases). This price may be higher than misoprostol tablets purchased locally, but the drugs are of known quality, and the combined regimen is significantly more effective than misoprostol used alone. Women Help Women ( https:// ) and Safe2Choose ( https:// ) also provide safe access to abortion medication.
Progestins , the most important of which is progesterone , are the other type of female sex hormone and are named for their role in maintaining pregnancy (pro- gestation ). Estrogens and progestins are secreted cyclically during menstruation . During the menstrual cycle , the ruptured ovarian follicle (the corpus luteum ) of the ovary produces progesterone, which renders the uterine lining receptive to the implantation of a fertilized ovum . Should this occur, the placenta becomes the main source of progesterone, without which the pregnancy would terminate. As pregnancy progresses, placental production of progesterone increases, and these high doses suppress ovulation , preventing a second conception . The contraceptive quality of progesterone led to the development of structurally modified progestins and estrogens—the oral contraceptives known as birth-control pills, used by women to prevent unwanted pregnancy.