It is known to act on the GABA A receptors in rat cells in vitro  as well as having antifungal properties.  Magnolol has a number of osteoblast-stimulating and osteoclast-inhibiting activities in cell culture and has been suggested as a candidate for screening for anti-osteoporosis activity.  It has anti-periodontal disease activity in a rat model.  Structural analogues have been studied and found to be strong allosteric modulators of GABA A .  Magnolol is also binding in dimeric mode to PPARγ , acting as an agonist of this nuclear receptor.