Zycortal® (Dechra Veterinary Products) is indicated for replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism. Zycortal contains desoxycortone pivalate (DOCP) – an aldosterone analogue with purely mineralocorticoid effect. Zycortal is available as a prolonged-release suspension for subcutaneous injection and the dosing interval is approximately 25 days. The exact dose to be given and the interval between treatments depend on the dog’s clinical response as well as sodium and potassium levels. A glucocorticoid (. prednisolone) is also needed daily to replace the missing cortisol. To obtain a Monitoring and Dose Adjustment Flowchart, or for further advice, contact Dechra by e-mailing technical@.
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Feeding fruit regularly is beneficial not only because it simulates the gaps in primary food availability that a dog would experience in nature, but for what fruits don't contain: namely, excess fat, stored toxins, nutrient imbalances, etc. Even when dogs are raw-fed, the foods that are produced in the modern meat industry cant ideally meet their nutritional needs because they don't precisely resemble what wild dogs have eaten throughout their history. For example, humans have developed methods that produce food animals with a higher than natural ratio of muscle to bone. Wild birds that are capable of flying hundreds of miles have tiny breast muscles, while modern domestic poultry that cant fly at all have huge mutated chests that are only good for one thing – feeding humans. These manipulations create nutritional excesses or imbalances in those who eat them, even when the consumer is a carnivore.